thanks for asking. I've had the same question in an email I just 
answered, so please accept my apologies for shamelessly copy and 
pasting it here:

-- cut -- 
Please note that the Wiimote driver is still in experimental state.

Apart from that, please make sure the "Bluetooth Receiver" is showing 
an active (green) state in the RB menu that you can access in the 
system's menu bar. You can also make Remote Buddy look for your 
Wiimote at startup by checking the respective checkboxes in 
"Preferences > Hardware > Bluetooth Receiver".

Another common error source are empty - or near empty - batteries. If 
you have another pair of batteries around of the ones you use are 
rechargable: give it a try. 
-- cut --

Hope that helps.

Best regards, 
Felix