thanks for your question.

Just to be sure: are you by any chance running Leopard or the Apple TV 
"BackRow"?

If not, which system version and hardware do you use - and how did you 
install Front Row?

Do you use any kind of AppleScript or anything else than Cmd+Esc or 
Remote Buddy's menu to switch to Front Row?

(from experience, Front Row does not seem to like being launched by 
AppleScript or by any other, traditional launcher mechanism - Remote 
Buddy thus doesn't make use of any of these)

Best regards, 
Felix