- Remote Buddy doesn't change any network settings 
- Remote Buddy uses Apple's official CFNetwork high-level APIs for the 
AJAX Remote and stays completely away from any low-level network stuff 
- Remote Buddy sure enough leaves your WLAN and WLAN drivers alone.

The only thing that I could think of is purely physical: if you are 
using a Bluetooth remote control and WLAN at the same time, the 
signals of both may interfere if they should use related/the same 
radio frequencies. But that's nothing Remote Buddy or any other 
software could have, has or will have any influence on. You may want 
to try to turn Bluetooth off and see if it helps.

It could also be a WLAN driver issue. Apple's discussions boards and 
Mac forums are full of them. And many of them are both long standing 
and unfixed.

Best regards, 
Felix