please make sure you run the latest version of Remote Buddy. Previous 
versions used the raw data coming from the remote to interpolate the 
mouse cursor position.

The latest versions now have a three-pass (!) filtering and smoothing 
algorithm that gives a very stable mouse functionality.

It is essential, though, that your sensor bar is strong and stable 
enough. You can check whether it is in Remote Buddy's preferences. 
When the mouse mode is active, you can see what the IR sensor of the 
WiiMote is seeing. If the red spots are tiny or blink when moving, 
your IR source is too weak for that distance.

Best regards, 
Felix Schwarz