Thanks for the quick reply. Changing remote in Plex to Apple and then back to Harmony did the trick, and when I tried to map buttons again for the Plex behaviour according to your instructions, it worked fine, the Harmony is back to normal. I do not know what I did the first time round, but clearly Plex Helper somehow lost access to the remote.

I have issues with getting my Mac to sleep, it often goes asleep for two seconds, and then comes back on again without activating the display. I saw some post here in the past about this, but I am not sure what and if Remote Buddy can help me here. any advice would be appreciated while I am trying out RB, getting the sleeping and waking up right would be a great contribution.

Whie I am trying understand what RB could add to my Harmony setup, I was wondering whether I could add any RB supported remote to my Harmony activity and assign default RB actions to some of its keys, and use these keys in my Harmny activity to bring up RB menu while in Plex?

Any other advice for what RB could bring to the table for a Harmony user would be very interesting for me!

Thanks, Henrik