As for me, I bought the Nintendo remote WiiPlus it a couple of weeks ago on Amazon. Since no solution was found to make it work with RemoteBuddy, I returned it and purchased a Harmony Remote 900 which works great natively with Plex. Unfortunately, it doesn't work as well when using it through Remote Buddy even with all the complex configuration steps with the 12 virtual remotes, etc.. Remote Buddy does control Plex for the most basic functions, but the more advanced buttons don't work as well, so I had to give up on RemoteBuddy for the time being, unfortunately.

Best regards, 
Jean-Charles Mourey