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Hi Felix,
Thank you for the rapid and informative response; sorry that my response is so long in coming. First, I apologize if the tone of my last post was negative, I was quite disappointed when I posted. I shouldn't have jumped to the conclusion that the "Restore to Defaults" button was the cause of all the menus being reset; I should know that correlation doesn't mean there is direct causation (post hoc ergo propter hoc).
Thank you for the suggestion about the quick Plex method. I guess that I should have better explained myself in my original post: I used the "Plex Player" behavior in the Logitech database as a method to address all the keys on my Harmony 880; I actually don't use Plex on my Mini HPTC. The result of the "Plex Player" behavior is 10 virtual Apple remotes, with button presses corresponding to each of the 40+ buttons on my Harmony.
I completely understand why you don't directly support the Harmony remotes; Logitech's code database for the Apple remote leaves something to be desired. I often have problems with the Harmony remote registering multiple button presses, no button presses, or delayed button presses.
I guess that my original question still stands: is there a way to quickly un-map default behaviors when adding multiple virtual remotes? With 10 virtual remotes, each mapped to around six different key presses, for 18 different behaviors... it takes significant time to un-map, then re-map all the key presses.
Thanks again for the great product and for the equally great support.
~Jordan